Top 10 Top 10 Most Fuel-Efficient Hybrid Cars by Frédéric Mercier May 20, 2019 Photo: Toyota2. Toyota PriusThe Toyota Prius introduced North American drivers to hybrid cars when it launched here more than 20 years ago. Even today, it ranks as one of the most fuel-efficient with a combined rating of 4.4 L/100 km. « PreviousNext » Share on Facebook Share: